Multifunctional Bilayer Nanocomposite Guided Bone Regeneration Membrane

Novel membrane for guided bone regeneration.

Membranes have been clinically used for guided tissue and bone regeneration for decades, but their use in every day clinical practice is rather limited. We developed a biodegradable membrane (InionGTR) composed of polylactide, polyglycolide and trimethylene carbonate aiming to improve the properties of membrane. Before application the membrane is treated with N-methyl-pyrrolidone (NMP) to achie...

Guided bone regeneration: A literature review

Guided bone regeneration (GBR) is a reconstructive procedure of alveolar ridge using membranes. This procedure is indicated when there is no sufficient bone for implantation, or in the case of optimal implant installation for esthetic or functional needs. GBR can be performed before implant placement, when there is not enough bone for initial stability of implants and less predictable outcomes ...

Bilayer Poly(Lactic-co-glycolic acid)/Nano-Hydroxyapatite Membrane with Barrier Function and Osteogenesis Promotion for Guided Bone Regeneration

Guided bone regeneration (GBR) is one such treatment that reconstructs neo-bone tissue by using a barrier membrane to prevent the invasion of soft tissue and to create a space for guiding new bone growth into the bone defect. Herein, we report a novel functionally graded bilayer membrane (FGBM) for GBR application. To fabricate the novel membrane, the composites of poly(lactic-co-glycolic acid)...

Advanced Nanocomposite Scaffold for Bone Regeneration

Introduction Each year in the United States approximately 500,000 procedures that involve the use of bone substitutes are performed. To address the limitations of materials currently used in orthopaedic tissue engineering, we have developed novel nanocomposite materials that consist of a citric acid-based elastomer, poly(1,8 octanediol citrate) (POC) and bioceramic nanoparticles, βtricalcium ph...

Nanocomposite Based Multifunctional Coatings